Monday, July 1, 2013

GOP Maj. Leader Eric Cantor On NSA And Investing In Small Government Technology

eric-cantor-portraitThe House Republican Majority Leader and Congressman with the most charming southern drawl,?Eric Cantor,?sat down with me at The Atlantic's Aspen Ideas Festival for an interview on the National Security Agency, Immigration, and the conservative case for supporting government-funded technology.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/dlIpckSNEhU/

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PFT: Gay former NFL player felt safest at work

HernandezAP

As the nonstop developments in the Aaron Hernandez murder case(s) begin to subside, it?s time to broaden the lens and address a topic that has popped up from time to time over the past two weeks.

Should the Patriots have avoided drafting Hernandez in 2010 and/or giving him a long-term, big-money contract in 2012?

Many are suggesting that the Pats screwed the proverbial pooch on this one, that they negligently brought a potential murderer to Massachusetts and, two years later, made him a multi-multi-millionaire.? But there are multi-problems with that logic.

For starters, there really was no indication that Hernandez was anything other than a kid who:? (1) liked to smoke marijuana; and (2) periodically made mischief.? As the folks at CFT pointed out on Saturday, Hernandez was indeed questioned in connection with a shooting nearly six years ago in Gainesville.? But it was perfunctory and brief.? Other Gators were questioned at the time, including safety Reggie Nelson and the Pouncey twins.

The only true red flag that attached to Hernandez from his college days came from an affinity for inhaling the fumes of a plant that, if anything, make the user less likely to commit violence or do anything other than sit around and eat Fritos.? And if there?s a link between smoking pot and murder, there would be a lot more murders.

Whatever was wrong with Hernandez, he supposedly had been rehabilitated by former Florida coach Urban Meyer, who according to the New York Times personally conducted ?daily Bible sessions? with Hernandez in order to turn him around.? Meyer presumably vouched for Hernandez to Patriots coach Bill Belichick.? Given the strong friendship between Belichick and Meyer that likely went a long way to persuading Belichick that Hernandez?s talents justified the risk.

Of course, some are now painting the picture that Hernandez entered the NFL with a pair of six-guns strapped to his side and ink on his arms that not-so-cryptically spelled out plans for his future crime sprees.? But where we these ?sources? with knowledge of supposed gang ties and other actual or perceived misdeeds or antisocial tendencies when Hernandez emerged as a fourth-round star in his second NFL season?

That would have been the obvious time for scouts, General Managers, and coaches to cover their collective asses by leaking the notion that, even though Hernandez was playing at a very high level, they avoided Hernandez in rounds one through three because he had more problems than marijuana.? But there was nothing ? not until after Hernandez was tied to a murder case and scouts and sources and some in the media all began to join in a hands-across-Whoville chorus of I told you so.

Even if Hernandez?s antics had generated real warning signs beyond marijuana, it?s impossible to connect dots from off-field misbehavior to premeditated murder.? It?s far more reasonable (or, as the case may be, far less reckless) to connect a substance-abuse problem (drugs or alcohol) to the potential for accidental death or dismemberment while driving a car.

Murderers come from all walks of life, with no way to prospectively screen for them ? unless they?ve actually killed in the past.? For every Aaron Hernandez there?s a Jovan Belcher, who generated no objective evidence to suggest that he would get into serious trouble before he repeatedly shot the mother of his young child and then killed himself in the presence of his coach and G.M.? Ditto for Rae Carruth, who orchestrated the murder of the mother of his unborn son because Carruth apparently didn?t want to pay child support.? The Chiefs and the Panthers saw neither problem coming, because there?s rarely any reason to suspect someone of having the capacity to deliberately kill someone else, regardless of the person?s history.

For the best proof of this, look no farther than O.J. Simpson.? Revered as a player, beloved as a broadcaster, and celebrated as an actor, he would have been the last man anyone would have regarded as the potential murderer of his ex-wife and a stranger who was in the worst possible place at the worst possible time.? (Simpson was acquitted in criminal court, but found legally responsible in civil court for the deaths of Nicole Brown Simpson and Ronald Goldman.)

On one hand, this is an extreme example of how the Modified Patriot Way of buying low ? via trades, free agency, and the draft ? can go very wrong.? On the other hand, the only way to avoid blame for harboring a potential murderer is to shun any player who has generated at any time any reason to believe that he could do anything wrong as an NFL player.

Even then, there?s still a chance that a player with no red flags will be the next Jovan Belcher, Rae Carruth, or O.J. Simpson.

Source: http://profootballtalk.nbcsports.com/2013/06/30/gay-former-nfl-player-said-he-felt-safest-at-work/related/

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Teddy Williams camp brings NFL to East Texas

POSTED: Saturday, June 29, 2013 - 8:44pm

UPDATED: Saturday, June 29, 2013 - 8:46pm

Former John Tyler Lion Teddy Williams held his speed and quickness camp Saturday at All-Saints.

The free camp is a chance for area kids to learn athletic skills from NFL players.

Williams brought NFL stars from the Falcons, Browns,?Seahawks, Bears and Cowboys to help coach the camp.

The All-American sprinter from UTSA says he loves putting the event on for free, because he knows a lot of these kids could not afford to go to a pay camp.

Williams played two years for the Cowboys before being released after the 2012 camp.

He finished the season with the Colts, and will head to camp with the team in July.

Source: http://www.ketknbc.com/sports/teddy-williams-camp-brings-nfl-to-east-texas

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Biomarker predicts risk of breast cancer recurrence after tamoxifen treatment

June 29, 2013 ? A biomarker reflecting expression levels of two genes in tumor tissue may be able to predict which women treated for estrogen-receptor (ER)-positive breast cancer should receive a second estrogen-blocking medication after completing tamoxifen treatment. In their report being published online in the Journal of the National Cancer Institute, Massachusetts General Hospital (MGH) Cancer Center investigators describe finding that the HOXB13/IL17BR ratio can indicate which women are at risk for cancer recurrence after tamoxifen and which are most likely to benefit from continuing treatment with the aromatase inhibitor letrozole (Femara).

"Most patients with early-stage, ER-positive breast cancer remain cancer-free after five years of tamoxifen treatment, but they remain at risk of recurrence for 15 years or longer after their initial treatment," says Dennis Sgroi, MD, of the MGH Cancer Center and Department of Pathology, lead and corresponding author of the report. "Our biomarker identifies the subgroup of patients who continue to be at risk of recurrence after tamoxifen treatment and who will benefit from extended therapy with letrozole, which should allow many women to avoid unnecessary extended treatment."

Previous research by Sgroi's team, in collaboration with investigators from bioTheranostics Inc., discovered that the ratio between levels of expression of two genes -- HOXB13 and IL17BR -- in tumor tissue predicted the risk of recurrence of ER-positive, lymph-node-negative breast cancer, whether or not the patient was treated with tamoxifen. The current study of patients from MA.17, the highly successful clinical trial of letrozole, was designed to evaluate the usefulness of the HOXB13/IL17BR ratio for both prognosis -- predicting which tamoxifen-treated remained patients at risk of recurrence -- and for identifying who could benefit from continued treatment with letrozole.

To answer those questions the investigators analyzed primary tumor samples and patient data from the placebo-controlled MA.17 trial, which confirmed the ability of extended letrozole therapy to improve survival after the completion of tamoxifen treatment. Tissue samples were available from 83 patients whose tumors recurred during the study period -- 31 who had received letrozole and 52 in the placebo group -- and 166 patients with no recurrence, 91 of whom had received letrozole, with 75 getting the placebo. Analysis of the tumor samples revealed that a high HOXB13/IL17BR ratio -- meaning the expression level of HOXB13 is greater than that of IL17BR -- predicts an increased risk for tumor recurrence after tamoxifen therapy, but that elevated risk drops significantly if a patient receives letrozole

Paul E. Goss, MD, PhD, director of the Breast Cancer Research Program at the MGH Cancer Center and a co-author of the report, explains, "This discovery means that about 60 percent of women with the most common kind of breast cancer can be spared unnecessary treatment with the concommitant side effects and costs. But more importantly, the 40 percent of patients who are at risk of recurrence can now be identified as needing continued therapy with letrozole, and many will be spared death from breast cancer." He and Sgroi note that their findings need to be validated by additional studies before they can be put into clinical practice.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/kFmW4R0U9Fo/130629164733.htm

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Sunday, June 30, 2013

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Hi,I got 94.5% marks in commerce stream.Do i have any chance to get admission in hindu college?

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Talks with Palestinians unlikely despite Kerry bid: Israeli minister

JERUSALEM (Reuters) - A senior Israeli official on Saturday played down the prospect of shuttle diplomacy by U.S. Secretary of State John Kerry reviving long-stalled peace negotiations with the Palestinians.

Asked whether new talks might be imminent, Civil Defense Minister Gilad Erdan, a member of Prime Minister Benjamin Netanyahu's security cabinet, told Israel's Channel Two television: "To my regret, no, as of now."

He blamed "preconditions" set by Palestinian President Mahmoud Abbas, whom Kerry met in Jordan twice in two days, alternating the meetings with talks with Netanyahu in Jerusalem.

(Writing by Dan Williams; Editing by Kevin Liffey)

Source: http://news.yahoo.com/talks-palestinians-unlikely-despite-kerry-bid-israeli-minister-164156947.html

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Monday, June 24, 2013

Ohio air crash shows risks, thrill of wing walking

A stunt plane loses control as a wing walker performs at the Vectren Air Show just before crashing, Saturday, June 22, 2013, in Dayton, Ohio. The crash killed the pilot and the stunt walker instantly, authorities said. (AP Photo/Thanh V Tran)

A stunt plane loses control as a wing walker performs at the Vectren Air Show just before crashing, Saturday, June 22, 2013, in Dayton, Ohio. The crash killed the pilot and the stunt walker instantly, authorities said. (AP Photo/Thanh V Tran)

Flames erupt from a plane after a stunt plane crashed while performing with a wing walker at the Vectren Air Show, Saturday, June 22, 2013, in Dayton, Ohio. The crash killed the pilot and the wing walker instantly, authorities said. (AP Photo/Thanh V Tran)

A wing walker performs at the Vectren Air Show just before crashing, Saturday, June 22, 2013, in Dayton, Ohio. The crash killed the pilot and the stunt walker instantly, authorities said. (AP Photo/Thanh V Tran)

Flames erupt from a plane after it crashed at the Vectren Air Show at the airport in Dayton, Ohio. The crash killed the pilot and stunt walker on the plane instantly, authorities said. (AP Photo/Dayton Daily News, Ty Greenlees)

This photo provided provided WHIO TV shows a plane after it crashed Saturday, June 22, 2013, at the Vectren Air Show near Dayton, Ohio. There was no immediate word on the fate of the pilot, wing walker or anyone else aboard the plane. No one on the ground was hurt. (AP Photo/WHIO-TV)

(AP) ? Risking death every time they go to work, wing walkers need courage, poise, a healthy craving for adrenaline and, most importantly, they need to be meticulously exacting with every step they take on the small planes that carry them past dazzled crowds at speeds up to 130 mph.

Jane Wicker fit that bill, her friends and colleagues in the air show industry said Sunday.

Wicker, 44, and pilot Charlie Schwenker, 64, were killed Saturday in a fiery plane crash captured on video at a southwestern Ohio air show and witnessed by thousands. The cause of the crash isn't yet known.

Jason Aguilera, the National Transportation Safety Board investigator leading the probe into the crash, said Sunday that it was too early to rule anything out and that the agency would issue its findings in six months to a year.

Wicker, a mother of two teenage boys and recently engaged, sat helplessly on the plane's wing as the aircraft suddenly turned and slammed into the ground, exploding on impact and stunning the crowd at the Vectren Air Show near Dayton. The show closed shortly afterward but reopened Sunday with a moment of silence for the victims.

The crash drew attention to the rarefied profession of wing walking, which began in the 1920s in the barnstorming era of air shows following World War I.

The practice fell off the middle of the 20th century but picked back up again in the 1970s. Still, there are only about a dozen wing walkers in the U.S., said John Cudahy, president of the Leesburg, Va.-based International Council of Air Shows.

Teresa Stokes, of Houston, said she's been wing walking for the past 25 years and does a couple of dozen shows every year. The job mostly requires being in shape to climb around the plane while battling winds, she said.

"It's like running a marathon in a hurricane," Stokes said. "When you're watching from the ground it looks pretty graceful, but up there, it's happening very fast and it's high energy and I'm really moving fast against hurricane-force winds."

Stokes, an aerobatic pilot before becoming a wing walker, said she was attracted to performing stunts because of the thrill.

"It is the craziest fun ride you've ever been on," she said. "You're like Superman flying around, going upside-down doing rolls and loops, and I'm just screaming and laughing."

John King, pilot and president of the Flying Circus Airshow, where Wicker trained, said the most important qualities of wing walkers are "strong nerves, a sense of adventure and a level head."

He said they tell people who are interested that it'll take a year of training before they'll be allowed to walk on the wing of an airplane in flight.

"We give them an opportunity to walk on a wing down on the ground without the engine running," he said. "Then we start up the engine. And if that doesn't spook them, OK, we taxi around the field and that's when it gets bumpy. If they do that successfully, the next time they do it is in the air."

He described Wicker, of Bristow, Va., and Schwenker, of Oakton, Va., as "ultimate professionals."

"I don't know of anyone who could have done any better than what they were doing," he said.

In one post on Wicker's website, the stuntwoman explains what she loved most about her job.

"There is nothing that feels more exhilarating or freer to me than the wind and sky rushing by me as the earth rolls around my head," says the post. "I'm alive up there. To soar like a bird and touch the sky puts me in a place where I feel I totally belong. It's the only thing I've done that I've never questioned, never hesitated about and always felt was my destiny."

She also answered a question she said she got frequently: What about the risk?

"I feel safer on the wing of my airplane than I do driving to the airport," she wrote. "Why? Because I'm in control of those risks and not at the mercy of those other drivers."

An announcer at Saturday's event narrated as Wicker's plane glided through the air.

"Keep an eye on Jane. Keep an eye on Charlie. Watch this! Jane Wicker, sitting on top of the world," he said, right before the plane made a quick turn and nosedive.

Some witnesses said they knew something was wrong because the plane was flying too low and slow.

Thanh Tran, of Fairfield, said he could see a look of concern on Wicker's face just before the plane went down.

"She looked very scared," he said. "Then the airplane crashed on the ground. After that, it was terrible, man ... very terrible."

From 1975 to 2010, just two wing walkers were killed, one in 1975 and another in 1993, Cudahy said. But since 2011, three wing walkers have died, including Wicker.

In 2011, wing walker Todd Green fell 200 feet to his death at an air show in Michigan while performing a stunt in which he grabbed the skid of a helicopter. That same year, wing walker Amanda Franklin died after being badly burned in a plane crash during a performance in South Texas. The pilot, her husband, Kyle, survived.

FAA spokeswoman Lynn Lunsford said the agency is often asked why wing walking is allowed.

"The people who do these acts spend hours and hours and hours performing and practicing away from the crowd, and even though it may look inherently dangerous, they're practiced in such a way that they maintain as much safety as possible," he said. "The vast majority of these things occur without a hitch, so you know whenever one of them goes wrong and there's a crash, it's an unusual event."

___

Associated Press writer Verena Dobnik in New York contributed to this report.

___

Follow Amanda Lee Myers on Twitter at https://twitter.com/AmandaLeeAP

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-06-23-Air%20Show%20Crash/id-9e8f038214f74f869c66843e076db14d

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'Supermoon' science: Biggest full moon of 2013 explained

Skywatcher Roberto Porto took this photo of the biggest full moon of 2012, a so-called supermoon, in Costa Adeje, Tenerife, Spai

Skywatcher Roberto Porto took this photo of the biggest full moon of 2012, a so-called supermoon, in Costa Adeje, Tenerife, Spain, on May 5, 2012.

By Miriam Kramer, Space.com

There is more to a "supermoon" than meets the eye.

Science governs the appearance of the largest full moon of the year,?and this weekend you can check out the amazing lunar sight for yourself.

On Sunday (June 23), the moon will be at its closest point to Earth ? called perigee. This relatively close brush will happen as the moon enters its fullest phase, creating the cosmic coincidence known as the supermoon. At its fullest and closest, the moon will appear about 12 percent larger in the sky. [Amazing Supermoon Photos of 2012]?

"It doesn't matter where you are, the full moon you're seeing will be the biggest for 2013," Michelle Thaller, the assistant director of science at NASA's Goddard Space Flight Center said. "? That 12 percent size different can mean as much as a 30 percent change in the brightness, so this will be a particularly bright supermoon."

How to see the supermoon
Weather permitting, everybody should be able to see the supermoon. The moon will be rising from the east right around sunset, Thaller said. It will appear huge and low on the horizon before rising brightly into the sky for the night. Saturday and Sunday should both be ideal viewing opportunities.

You can also watch a live webcast of the supermoon on SPACE.com beginning on Sunday beginning at 9 p.m. EDT (0100 June 24 GMT), courtesy of the online Slooh Space Camera, an online skywatching website (http://www.slooh.com).

?The full moon is seen as it rises near the Lincoln Memorial, Saturday, March 19, 2011, in Washington. The full moon tonight is called a super perigee moon since it is at its closest to Earth in 2011. The last full moon so big and close to Earth occurred in March 1993.

A changing distance
Supermoons occur about once annually, and this year, the supermoon is closer than it has been in a little while, Thaller said.

The distance from the Earth to the moon varies along the rocky satellite's elliptical orbit. Perigee differs from month to month, so sometimes the supermoon is a little closer or further away, Thaller said.

"The closest the moon gets can actually vary much as much as the diameter of the Earth," Thaller said. "That seems like a pretty big number, but the moon is actually 30 times the diameter of the Earth away from us. If you line up 30 Earths, that's about the average distance of the moon away, but as it swings a little bit closer to us, that distance can vary."

Moon Master: An Easy Quiz for Lunatics For most of human history, the moon was largely a mystery. It spawned awe and fear and to this day is the source of myth and legend. But today we know a lot about our favorite natural satellite. Do you?For most of human history, the moon was largely a mystery. It spawned awe and fear and to this day is the source of myth and legend. But today we know a lot about our favorite natural satellite. Do you? ??0 of 10 questions complete Start Over

Science from a moon
Although it might be a brilliant skywatching opportunity, not a lot of scientific research comes from the supermoon. Scientists prefer to study the moon from a closer vantage point, Thaller said.

"The supermoon for [scientists] is a fun chance to talk about the changes in the sky [and] observing the universe," Thaller told SPACE.com. "As scientists, we like to observe the moon a little bit closer up and right now we have LRO, the Lunar Reconnaissance Orbiter, a spacecraft actually orbiting the moon. We're taking these incredible high resolution pictures of the entire lunar surface."

Editor's note: If you snap an amazing photo of the Sunday supermoon and you'd like to share it for a possible story or image gallery on SPACE.com, please send images and comments, including equipment used, to managing editor Tariq Malik at spacephotos@space.com.

Follow Miriam Kramer?@mirikramer?and?Google+. Follow us?@Spacedotcom,?Facebook?and?Google+. Original article on?SPACE.com.

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Source: http://feeds.nbcnews.com/c/35002/f/653377/s/2da6d983/l/0Lscience0Bnbcnews0N0C0Inews0C20A130C0A60C220C190A913130Esupermoon0Escience0Ebiggest0Efull0Emoon0Eof0E20A130Eexplained0Dlite/story01.htm

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Wikileaks says helped Snowden find 'political asylum in a democratic country'

HONG KONG (Reuters) - The Wikileaks anti-secrecy website said on Sunday it helped a former contractor for the U.S. National Security Agency, charged by the United States with espionage, to leave Hong Kong and find "political asylum in a democratic country".

Edward Snowden, 30, left for Moscow on Sunday and his final destination may be Ecuador or Iceland, the South China Morning Post said.

WikiLeaks founder Julian Assange said last week he would not leave the sanctuary of the Ecuadorean Embassy in London even if Sweden stopped pursuing sexual assault claims against him because he feared arrest on the orders of the United States.

(Reporting by Nishant Kumar in Hong Kong; Writing by Nick Macfie; Editing by Clarence Fernandez)

Source: http://news.yahoo.com/wikileaks-says-helped-snowden-political-asylum-democratic-country-091221559.html

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Discovery Communications' John Hendricks: From Huntsville to ...

"Why can't this be on TV? That was in Huntsville at UAH. That was a lingering question that was on the road to the Discovery Channel."

HUNTSVILLE, Alabama - John Hendricks was a history student at the University of Alabama in Huntsville in the 1970s when he had an idea that would change television. Today, Hendricks is the founder and chairman of Discovery Communications, a worldwide empire with more than 100 channels and 1.5 billion viewers. Then, he was a work-study student helping his professors find documentaries to screen in their classes.

"As I was looking through all this volume of catalogs for documentary films that were available, I just had this question," Hendricks said in an interview this month. "Why can't this be on TV? That was in Huntsville at UAH. That was a lingering question that was on the road to the Discovery Channel."

Hendricks looks back at building Discovery and growing up in Alabama during the space race and the Civil Rights Era in the new memoir "A Curious Discovery: An Entrepreneur's Story" being published June 25 by HarperCollins. The book tells the stories behind some of the Discovery networks' most popular shows, including "Trading Spaces," "The Crocodile Hunter" and "Here Comes Honey Boo Boo," and it's a how-to manual for would-be entrepreneurs.

In the book, Hendricks writes about his bad business moves as well as his good ones, including the day Discovery faced bankruptcy because his sole source for a new round of funding said "no" at the last moment. "All that counted was the Chronicle investment was dead," he writes, "and stupidly, I now realized, I had failed to use the intervening months to solicit any other investor prospects."

"For something to be useful, people need to know the whole story," Hendricks said this month. "If you're going to have three or four successes in your life, you've probably had five to 10 significant failures."

The book contains enough detail about Hendricks' path to be studied at business schools, but a man who has worked with everyone from Walter Cronkite and "Crocodile Hunter" Steve Irwin to Oprah Winfrey also has stories to tell. Among others, he recounts the terrible day he learned Irwin had died from stingray barb, and he takes readers inside his long, close relationship with Walter Cronkite.

Some of Hendricks' best stories involve expanding Discovery's portfolio from documentaries aimed at 25 percent of the viewing public - his original audience - to reality programs like "Trading Spaces," and, eventually, shows like "Here Comes Honey Boo Boo." Now, Discovery is now a major source, under its different network banners, of programs not too far from ones Hendricks once dismissed as "Tattoo TV."

Part of the reason for the stretch was economic, and again Hendricks is direct. "For us to be a global force in programming and to have the resources that we can continue to undertake very expensive productions like 'North America, which is now running on Discovery," he said in the interview, "we have to break beyond that 25 percent and reach over and develop a portfolio of networks that also work within (the) amusement and entertainment platforms."

But Hendricks has come to appreciate reality TV in all of its dimensions, and he said that happened in stages. First, Hendricks said he realized that shows about people like Cake Boss Buddy Valastro and Georgetown Cupcake founders Katherine Berman and Sophie LaMontagne were not only incredibly popular, but inspirational. They tell the stories of legitimate American entrepreneurs whose paths aren't that different from Hendricks' own. Later, Hendricks said he came to see shows about different, even exotic lifestyles - whether Amish teenagers or Honey Boo Boo - as legitimate ways to satisfy legitimate viewer curiosity about their world.

Hendricks was careful to put a fence around the original Discovery brand and spin off new networks to showcase new programming. He cites a big-time model for that, too.

"You can think of it this way," Hendricks said in the interview. "Disney Corp. has a wonderful legacy of that all-family brand of Disney, but at one point to be able to survive and grow and prosper, Disney had to be able in their motion picture business to offer R-rated films. So, they did that through a number of separate divisions and studios that they owned that didn't carry the Disney brand. For years, they owned Miramax and Touchstone and Hollywood Pictures."

Today, Hendricks stays busy with Discovery Communications and its ongoing challenges in a changing media world. When he's not in the corporate offices outside Washington, he's involved in developing Gateway Canyons, a Colorado resort designed to offer guests "curiosity adventures" on land protected from development. He travels for work and to satisfy his own curiosity - a recent trip to Tanzania included time spent with the last hunter-gather tribe in Africa - and visits Huntsville to see his brother-in-law Jim Sisson, lead engineer for the Apollo program's lunar rover, and his nephews Martin and Alan. Hendricks' sister, Linda, died some years ago.

Hendricks life in Huntsville echoes through the book, and longtime residents will enjoy his memories of Budd's and Bill's Men's Wear, clothing stores where he worked; the day Huntsville schools integrated in 1963; and his parents' pleasure at seeing his picture in The Huntsville Times for winning a local insurance agents' essay contest on "The Free Enterprise System."

"It's funny how the tiniest event can change the trajectory of one's life," Hendricks writes in his book. "Writing that essay was one of those moments, and I've often thought about how deeply it influenced everything that came after. Putting those few hundred words on paper forced me to really think about what motivates people to accomplish something in life, to invent or adapt new products, and to create experiences that did not exist before."

Hendricks says growing up in Huntsville was key to what he has accomplished.

"If you look through the book," he said in the interview, "there's a kind of continuing thread. I'm going to name-drop here, and I'm so sorry to do it, but Oprah had read the book and called me. And she said, 'John what you've done is a kind of business memoir, but what you've done is capture a thread: What was the thread that led to Discovery?'

"I have to say that Huntsville was just a big part of that thread," Hendricks said. "It was such an inspiring place to grow up."

Source: http://blog.al.com/breaking/2013/06/discovery_channels_john_hendri.html

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Jennifer Grace: Y.A.K.: You Always Know

2013-06-14-HappyWoman.jpeg

Sometimes it's a whisper. Other times, it's a scream.

But in all of us, there is a voice of wisdom to help guide us. It's called our intuition. We are all born with it, but like everything else, if we don't use it we lose it.

The secret to living wisely is to live intuitively.

So often, my students say to me, "I'm such a bad decision maker."

I tell them, "Life isn't made up of decisions; life is made up of experiences."

It is time to change our vocabulary. The root of "decision" -- literally, from a linguistic perspective -- is "to kill off." What we really need to talk about are choices: The ones we make, and how to make the right ones.

We all have the right to choose. If that choice doesn't work, or no longer resonates with us, we also have the right to choose again. Many of us are so fearful of making the wrong choice that instead of accessing our own wisdom, we take a poll.

When we stand at one of the great crossroads of life, instead of listening to our intuition, we listen to everyone else.

"What do you think I should do?"

We ask our mothers, our partners, even our therapists. The result? We get 20 different answers to the same question. Then we end up confused, stuck and unable to move forward in the best possible direction.

Even more frustratingly, we often hear competing advice from our own inner voice, too. We might hear "Follow your heart; go for it!" one moment and "Don't be a fool; that's too risky and you'll never succeed" the next.

That second voice is our inner critic, or what I lovingly refer to as our "Itty Bitty Shitty Committee." The committee, and our voice of wisdom, are fighting in a constant back-and-forth. It then becomes challenging to distinguish which voice is the one we should follow.

But, alas, there is hope!

There are many wonderful ways to cultivate your intuition and differentiate between the two. Once you clearly identify your intuitive voice, you can always trust it. It is mistake-free, and will never lead you astray.

You can cultivate that intuitive voice by journaling and meditating. When you give the intuitive voice a blank page to write on -- or a blank space of silence to center on -- you create a space for the voice to reveal itself to you.

Other ways of finding your voice of wisdom include taking some "alone time" in nature, to contemplate and listen. If your voice of wisdom is at work, you will feel calm, centered and relaxed. You'll soon learn the stark difference between this place of piece and the negative emotional charge that accompanies your "Itty Bitty Shitty Committee."

Remember: You always have the ability to guide yourself toward a destiny filled with what you desire and need. Just trust, and understand. The secret lies in three little letters: Y.A.K.: You Always Know.

For more by Jennifer Grace, click here.

For more on wisdom, click here.

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Follow Jennifer Grace on Twitter: www.twitter.com/BeHereGrace

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Source: http://www.huffingtonpost.com/jennifer-grace/inner-voice_b_3441511.html

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Tuesday, April 30, 2013

Researchers design nanometer-scale material that can speed up, squeeze light

Apr. 29, 2013 ? In a process one researcher compares to squeezing an elephant through a pinhole, researchers at Missouri University of Science and Technology have designed a way to engineer atoms capable of funneling light through ultra-small channels.

Their research is the latest in a series of recent findings related to how light and matter interact at the atomic scale, and it is the first to demonstrate that the material -- a specially designed "meta-atom" of gold and silicon oxide -- can transmit light through a wide bandwidth and at a speed approaching infinity. The meta-atoms' broadband capability could lead to advances in optical devices, which currently rely on a single frequency to transmit light, the researchers say.

"These meta-atoms can be integrated as building blocks for unconventional optical components with exotic electromagnetic properties over a wide frequency range," write Dr. Jie Gao and Dr. Xiaodong Yang, assistant professors of mechanical engineering at Missouri S&T, and Dr. Lei Sun, a visiting scholar at the university. The researchers describe their atomic-scale design in the latest issue of the journal Physical Review B.

The researchers created mathematical models of the meta-atom, a material 100 nanometers wide and 25 nanometers tall that combined gold and silicon oxide in stairstep fashion. A nanometer is one billionth of a meter and visible only with the aid of a high-power electron microscope.

In their simulations, the researchers stacked 10 of the meta-atoms, then shot light through them at various frequencies. They found that when light encountered the material in a range between 540 terahertz and 590 terahertz, it "stretched" into a nearly straight line and achieved an "effective permittivity" known as epsilon-near-zero.

Effective permittivity refers to the ratio of light's speed through air to its speed as it passes through a material. When light travels through glass, for instance, its effective permittivity is 2.25. Through air or the vacuum of outer space, the ratio is one. That ratio is what is typically referred to as the speed of light.

As light passes through the engineered meta-atoms described by Gao and Yang, however, its effective permittivity reaches a near-zero ratio. In other words, through the medium of these specially designed materials, light actually travels faster than the speed of light. It travels "infinitely fast" through this medium, Yang says.

The meta-atoms also stretch the light. Other materials, such as glass, typically compress optical waves, causing diffraction.

This stretching phenomenon means that "waves of light could tunnel through very small holes," Yang says. "It is like squeezing an elephant through an ultra-small channel."

The wavelength of light encountering a single meta-atom is 500 nanometers from peak to peak, or five times the length of Gao and Yang's specially designed meta-atoms, which are 100 nanometers in length. While the Missouri S&T team has yet to fabricate actual meta-atoms, they say their research shows that the materials could be built and used for optical communications, image processing, energy redirecting and other emerging fields, such as adaptive optics.

Last year, Albert Polman at the FOM Institute for Atomic and Molecular Physics in Amsterdam and Nader Engheta, an electrical engineer at the University of Pennsylvania, developed a tiny waveguide device in which light waves of a single wavelength also achieved epsilon-near-zero. But the Missouri S&T researchers' work is the first to demonstrate epsilon-near-zero in a broadband of 50 terahertz.

"The design is practical and realistic, with the potential to fabricate actual meta-atoms," says Gao. Adds Yang: "With this research, we filled the gap from the theoretical to the practical."

Through a process known as electron-beam deposition, the researchers have built a thin-film wafer from 13 stacked meta-atoms. But those materials were uniform in composition rather than arranged in the stairstep fashion of their modeled meta-atoms.

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The above story is reprinted from materials provided by Missouri University of Science and Technology. The original article was written by Andrew Careaga.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Lei Sun, Jie Gao, Xiaodong Yang. Broadband epsilon-near-zero metamaterials with steplike metal-dielectric multilayer structures. Physical Review B, 2013; 87 (16) DOI: 10.1103/PhysRevB.87.165134

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_technology/~3/RFnsUhSDhLc/130429094646.htm

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Friday, April 26, 2013

Contactually Puts Its SME Contacts Platform ?On Steroids' With Major New Update

Screen Shot 2013-04-25 at 18.12.14You're familiar with the scenario of not being able to keeping up with some of your best contacts because there are probably now plenty of them? Small businesses have that same problem, and they aren't about to employ heavy lifting CRM to solve that simple problem. Contactually, which has previously raised money form Point Nine Capital, Boston Seed and 500 Startups, is going to try to address this with a major new iteration of the platform it launched in 2011.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/cbYiEi1hQpE/

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CSN: O's extra-inning winning streak ends at 17

BALTIMORE ? For more than a year, the Orioles won extra inning games. Seventeen in a row.

At some point, the magic was going to end. Wednesday was the day.

After watching Josh Stinson serve up four home runs to put them in a hole, the Orioles clawed their way back into the game with Toronto, but finally lost it 6-5 in 11 innings before 14,981 at Oriole Park.

Stinson was recalled before the game and sent to Norfolk afterward. The Orioles bullpen was chewed up, and the most dependable of all the relievers, Jim Johnson suffered a loss.

?That's the type of baseball we play. It's just one of those things. We play a lot of close games and I wouldn't expect anything to change in that department,? Johnson said.

The Orioles (12-9) closed out a most successful home stand by winning two of three from the Blue Jays, Dodgers and Rays. The 6-3 record gave them an acceptable 9-6 mark against American League East opponents.

?I thought we played pretty well for the most part. It would have been nice to close today, but they got us today, but I think it was a pretty decent homestand overall,? Nate McLouth said.

Now, the Orioles head west for a season-long 11-game road trip to Oakland, Seattle and Los Angeles.

They?ll be there without Stinson and with another reliever, perhaps Zach Clark, who?s been starting for Norfolk.

Three of the homers allowed by Stinson were solo shots to Rajai Davis, Edwin Encarnacion and Jose Bautista. The first was a two-run shot by J.P. Arencibia in the second.

By the time Stinson left with two outs in the sixth, the Orioles trailed 5-2, but they scored three runs in the seventh to tie it.

?They came back and that's what I've been told about these guys. They never quit and they keep going. So they got us back to 5-5 and made it interesting for a couple innings. It was exciting,? Stinson said.

The Orioles had won 17 straight extra-inning games, their last 16 in 2012, and the first of this season. Only the 1959-60 Pittsburgh Pirates, who won 21 consecutive, won more.

?It's not something I dwell on. I know our guys don't. But I understand how it's noteworthy," manager Buck Showalter said.

In the 11th, Arencibia and Munenori Kawasaki singled with two outs off Johnson (1-2), who had won and saved the previous two games of the series..

Johnson hit Brett Lawrie with a pitch to load the bases and walked Macier Izturis on four pitches to score Arencibia with the go-ahead run for Toronto (9-13).

Esmil Rogers (1-1) pitched the 10th and got the win. Manny Machado tried to score on J.J. Hardy?s single in the bottom of the 10th, but was thrown out, and the game went to the 11th.

Casey Janssen pitched the 11th for his sixth save.

In 22 1/3 previous major league innings, Stinson allowed two home runs. He tripled that total on Wednesday.

Stinson retired the first three batters, and took a 1-0 lead into the second. Nate McLouth and Adam Jones doubled off Brandon Morrow in the second, and it was their last hit until the seventh.

Arencibia?s two-run shot to center, his eighth, came with one out in the second. Davis hit his first with one out in the second while Encarnacion and Bautista hit theirs leading off the fourth and sixth. It was Encarnacion?s fourth and Bautista?s fifth.

Stinson was hooked with two outs in the sixth. He allowed five runs on five hits in 5 2/3 innings. He walked one and struck out three.

The Orioles scored a run without a hit in the third. McLouth walked with one out. Machado grounded to third and Lawrie threw it wildly to first. McLouth advanced to third. Nick Markakis grounded to short, but? Machado slid hard enough into second baseman Emilio Bonifacio that he prevented any chance of a double play.

In the seventh, the Orioles finally showed some life. Nolan Reimold walked with one out. Ryan Flaherty doubled to right to score Reimold and Aaron Loup replaced Morrow.

McLouth singled to score Flaherty, and after McLouth stole his fifth base of the season, Machado tripled to right, and score was tied at 5.

?We didn?t play a bad game by any means. Their hits came with some damage. We weren?t quite able to push that last one across a couple of times,? McLouth said.

NOTES: The four home runs allowed by Stinson were the most by any Orioles pitcher making his debut.

-Machado?s triple was the first of the year for the Orioles.

-Brian Matusz has not allowed any of the 10 runners he inherited this season to score. He?s stranded all 24 he inherited since he became a reliever last August.

Source: http://www.csnbaltimore.com/blog/orioles-talk/orioles-extra-inning-streak-ends-blue-jays-loss

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Thursday, April 25, 2013

Study Finds Possible New Ally in Fight Against Diabetes

Researchers may have found a new helpmate in their search for a cure to diabetes. A new study in the journal Cell, published online on Thursday, has identified a particular hormone that appears to grow the very cells that are destroyed by the disease.

The hormone, which the scientists working on the study have dubbed betatrophin, encourages the pancreas to grow new beta cells. Beta cells are our body's primary manufacturers of insulin.

Here is some of the key information that emerged on Thursday regarding this new study into the effect of hormones on diabetes.

* People with diabetes lack the ability to make enough insulin, which helps the body process sugar. Without it, a person can eventually suffer from organ damage, kidney failure, and blindness, and can even lose a limb to the disease.

* As noted by Bloomberg News, this study was conducted in mice. In the mouse study, betatrophin increased the production of beta cells by more than 33 times.

* Douglas Melton, who is the co-director of the Department of Stem Cell and Regenerative Biology at Harvard University, told Bloomberg and other media outlets on Thursday that humans have a hormone that is almost identical to the mouse version of betatrophin, and that preliminary examination appears to indicate that it performs the same function in the human body that it does in mice.

* Harvard has applied to be able to patent betatrophin, and major drug companies around the world are already taking notice of the work being done by Melton and his colleagues.

* Melton told USA Today that he and his fellow researchers next want to create an injectable form of the hormone and use it to treat diabetic mice.

* Some in the scientific community are reserving judgement on the significance of Melton's team's findings until research is done with humans. Dr. Peter Butler, who researches diabetes at the University of California-Los Angeles, told USA Today on Thursday that research needs to be presented that shows that manipulating betatrophin in the human body will cause the pancreas to begin producing beta cells as it does in mice.

* Other researchers familiar with the work insist that Melton's findings may lead to new avenues of research and perhaps even new treatments for the disease. Mary-Elizabeth Patti of the Joslin Diabetes Center in Boston told NPR that she was certain that "this will stimulate a lot of work to look at the effects of this protein and rapidly investigate" its full potential.

* Betatrophin, if proven as an effective treatment, would be most effective for use in patients with Type 2 diabetes, according to Melton, due to differences between the Type 2 and Type 1 variations of the disease. Therapies for Type 1 diabetes may also be possible, he noted, but they would require different avenues of research into betatrophin.

Vanessa Evans is a musician and freelance writer based in Michigan, with a lifelong interest in health and nutrition issues.

Source: http://news.yahoo.com/study-finds-possible-ally-fight-against-diabetes-220500302.html

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Samsung Electronics profit jumps ahead of Galaxy S4 debut

SEOUL (Reuters) - Samsung Electronics Co Ltd reported on Friday its sixth straight quarter of profit growth ahead of the debut of its latest Galaxy smartphone, the South Korean IT giant's biggest assault on rival Apple Inc yet.

By launching the Galaxy S4 in the United States on Saturday, Samsung is taking aim at Apple's home market at a time when the iPhone maker appears to have hit a snag. Earlier this week, Apple reported its first profit decline in more than a decade and indicated no major product releases until the fall.

Samsung is widely expected to resume posting record quarterly profits, after a hiatus in January-March, as the S4 is dispatched to 327 mobile carriers in 155 countries.

This week, Samsung has kicked off a massive advertising campaign for the S4 and set up mini stores at Best Buy locations to promote the smartphone. Initial orders have surprised on the upside, with the firm expecting a short-term supply crunch.

Early success of the S4 is crucial in determining the extent of the expected second-quarter record earnings for a company that gets more than 70 percent of its overall profit from mobile devices.

The new S4, which sports a host of software-enabled features, is seen as stealing a head-start on what's widely expected to be an upgraded iPhone later this year. But the Galaxy phone has drawn mixed reviews so far.

Profit from Samsung's mobile division jumped 56 percent to a record 6.51 trillion won in the first quarter, accounting for nearly three quarters of the firm's entire profit, the company said on Friday, before the stock market open.

Samsung, which doesn't provide smartphone sales figures, likely sold 68-70 million smartphones in the quarter ended March, up from 63 million in the previous quarter, according to five analysts.

By contrast, second-ranked Apple said on Tuesday it shipped 37.4 million iPhones in the March quarter, up from 35.1 million a year ago, but down sharply from 47.8 million in the previous quarter.

Samsung's first-quarter overall operating profit increased 54 percent from a year ago to 8.8 trillion won ($7.9 billion), broadly in line with its earlier estimate and almost on par with the fourth-quarter's record of 8.84 trillion won.

Shares in Samsung, valued at around $215 billion, have risen 2 percent in the past three months, beating a 21 percent decline in Apple and a 1 percent drop in the wider market.

(Reporting by Miyoung Kim; Editing by Ryan Woo)

Source: http://news.yahoo.com/samsung-electronics-first-quarter-profit-jumps-ahead-galaxy-234822201--finance.html

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Stock index futures indicate higher open

LONDON (Reuters) - Stock index futures pointed to a higher open on Wall Street on Wednesday, with futures for the S&P 500, Dow Jones and Nasdaq 100 futures all up 0.2 percent at 0455 EDT ( 0855 GMT).

U.S. stocks climbed on Tuesday in a broad rally, recovering from sharp declines sparked by a "bogus" Associated Press tweet about explosions at the White House.

Wednesday's diary sees U.S. weekly mortgage market index and durable goods figures. Treasury Secretary Jack Lew also testifies in front of Congress.

Apple Inc on Tuesday bowed to investors' demands to share more of its $145 billion cash pile, while posting its first quarterly profit decline in more than a decade after market close yesterday. The tech giant initially rose in extended trade, then retreated after the company's chief executive suggested there would be no new product in the market for a few months.

KFC parent Yum Brands Inc on Tuesday reported that quarterly profit fell less than Wall Street expected, despite a sharp drop in sales in its top China market, sending the company's shares up nearly 6 percent in after hours trade.

Cable operator Virgin Media posted a 54 percent rise in first quarter free cash flow and announced a series of major business deals on Wednesday, showing the attraction of a company that is about to be sold to Liberty Global.

AT&T Inc reported a net loss of cellphone subscribers in the first quarter as it lost market share to bigger rival Verizon Wireless, sending its shares down about 2 percent in after hours trade.

OPKO Health Inc will buy Israel-based biopharmaceutical company Prolor Biotech Inc in an all-stock deal valued at $480 million to expand its portfolio of specialty drugs.

European shares gained on Wednesday, building on the best session of the year so far on Tuesday. Good earnings reports helped the market higher, while disappointing data from Germany over the last two days has lent strength to the case for the European Central Bank to cut interest rates next week.

(Reporting by Alistair Smout; editing by Patrick Graham)

Source: http://news.yahoo.com/wall-street-jumps-recovery-twitter-led-drop-012743441--sector.html

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Zinio Guest Post: Read A Digital Magazine; Save A Tree (or 104,000)

Earth Day should be everyday. If only the world would be a little more veggie, a bit more green, and read more digitally, we would be a much more sustainable and environmentally sound planet. And, we would save and sustain trees.

On a serious note, Zinio helps save more than 104,000 trees every month. And it contributes more wealth in terms of information and entertainment on our newsstand. We recognize we have a lot of magazines (over 5,500), but sometimes we look twice and realize we've aggregated more quality content in one arena or another than just about any source you can find. There's a lot of great writing and photography from a broad spectrum of journals from around the world. Zinio has something for everyone, whether it's the politics of global warming or just getting out and enjoying the natural world.

We?re celebrating in two ways this week. First, with a sale of over 100 titles at up to an additional 50 percent off www.zinio.com/reforest. And, we?ve created a content collection of some of our favorite magazines that support sustainable articles you can read for free here:

Sierra: It?s a lot more than the official magazine of the Sierra Club. Sierra is arguably the only magazine that can teach you how to fly. Its most recent issue features a series of stories on wind energy, including a piece on gear you can buy to harness the wind to literally fly. Get your wingsuit. What I love about Sierra digital are the great photos and the balance between caring for the environment and caring for the economy.

http://www.zinio.com/www/browse/product.jsp?rf=sch&productId=500618227

Green Ideas: The US market should have one of these. It?s a New Zealand-based magazine. But the practical and tactical content in Green Ideas are truly global. For me that, what digital publishing is all about: No borders. It?s A consumers? guide to living more sustainably ? loaded with ideas and practical advice for people who want to know more about the environment and minimize their impact on it.

http://www.zinio.com/www/browse/product.jsp?rf=sch&productId=500668739

Whole Living: Think Martha Stewart goes green. Whole Living puts a bit of a glitzy spin on eating with a healthy approach, entertaining with a green approach and looking into the ?healthy circle? of upscale communities that are living closer to the earth.

http://www.zinio.com/www/browse/product.jsp?rf=sch&productId=253430564&sch=true

Green Source: Another great case for digital publishing. I discovered this magazine while I was looking for some design advice for a home improvement project. I found this, which is a brilliant looking journal for professionals. Green Source covers sustainable design, green building case studies for architects, engineers, designers, contractors and owners. It might sound boring on the surface. But it feels like you?re being invited into an exclusive club.

http://www.zinio.com/www/browse/issue.jsp?skuId=416242264&prnt=&offer=&categoryId

Outside: This pick might be a little popular but you simply can?t ignore the excellence, writing and sheer visual power of Outside. The only thing its readers are more passionate about than working out and extreme sports is the environment. http://www.zinio.com/www/browse/product.jsp?rf=sch&productId=216990576&sch=true

Source: http://www.appolicious.com/tech/articles/13423-zinio-guest-post-read-a-digital-magazine-save-a-tree-or-104-000

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Cycle Safe | scoilmhuirecoole.scoilnet.ie

The 4th , 5th and 6th classes completed a Cycle Safe programme ran by Westmeath Sports Partnership.
This programme assists young people in gaining the skills and knowledge to safely cycle and hopefully encourage them into the world of cycling as a mode of transport, and as a source of recreation and sport.

Cycling is an ideal form of transport for young people providing a healthy, cheap and
environmentally friendly way to get about. The children enjoyed the programme and are now more confident cyclists.

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Source: http://scoilmhuirecoole.scoilnet.ie/blog/2013/04/23/cycle-safe-2/

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Wednesday, April 24, 2013

AT&T Q1 2013 earnings: $3.7 billion income on revenue of $31.4 billion

AT&T Q1 2013 earnings $37 billion income on revenue of $314 billion

AT&T just posted its earnings for the first quarter of 2013, and the market couldn't help but ding the company, which is now trading down in after hours markets. The business as a whole posted a net income of $3.7 billion, which is slightly up from $3.6 billion one year ago. Meanwhile, company revenues took a slight hit, which sit at $31.4 billion -- down 1.4 percent from the previous year. In terms of the company's wireless business, though, there's plenty of reason for optimism. The company was able to snag an additional 296,000 postpaid subscribers and put a solid 1.2 million people on smartphone plans during the quarter. For those keeping track, smartphone sales now account for 88 percent of AT&T's postpaid handsets. Unsurprisingly, the company is making more money than ever off of its data plans, which account for $5.1 billion of the company's business. As for the wireless segment as a whole, income is up 21 percent and AT&T is pulling in revenues of $16.6 billion with a 28 percent profit margin.

Encouraging signs were also revealed for U-verse, as the company's broadband service netted an additional 731,000 internet subscribers and 232,000 television subscribers during the quarter -- its best performance in two years -- for a grand total of 8.7 million subscribers. Naturally, one segment of Ma Bell's business isn't looking too hot, and that's the traditional wireline business, as revenues have fallen 10 percent from the previous year. Given the size of this segment, and the weakening demand for the service, it's easy to understand why investors might be slightly uneasy, even in light of all the encouraging news.

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Source: AT&T

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/_89FzC3DQTA/

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Before Midnight Poster: Arrived!

Source: http://www.thehollywoodgossip.com/2013/04/before-midnight-poster-arrived/

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Gut Microbe Makes Diesel Biofuel

Reconfiguring the genetics of the food pathogen E. coli produces hydrocarbons indistinguishable from those burned in trucks


e coli in petri dish E. coli can now replicate the hydrocarbon molecules that burn predominantly in big trucks and other powerful moving machines. Image: Flickr/Carlos de Paz

Welding bits and pieces from various microbes and the camphor tree into the genetic code of Escherichia coli has allowed scientists to convince the stomach bug to produce hydrocarbons, rather than sickness or more E. coli. The gut microbe can now replicate the molecules, more commonly known as diesel, that burn predominantly in big trucks and other powerful moving machines.

"We wanted to make biofuels that could be used directly with existing engines to completely replace fossil fuels," explains biologist John Love of the University of Exeter in England, who led the research into fuels. "Our next step will be to try to develop a bacterium that could be deployed industrially." Love?s work was published April 22 in Proceedings of the National Academy of Sciences.

That means harnessing E. coli's already high tolerance for harsh conditions, such as the high acidity and warmth of the human digestive tract. That hardiness also seems to be helping the bacterium survive its own production of such longer-chain hydrocarbons, which could have proved toxic to the microbes, in the way brewer's yeast cells are killed off by the alcohol they ferment. The engineered E. coli used genetic code from the insect pathogen Photorhabdus luminescens and from the cyanobacterium Nostoc punctiforme as well as soil microbe Bacillus subtilis to make the fuel molecules from fatty acids, along with a gene from the camphor tree?Cinamomum camphora?to cut the resulting hydrocarbon to the right length.

The E. coli are currently fed on sugar and yeast extract, which suggests that the resulting fuel would be expensive compared with the kind refined from oil found in the ground. "We are hopeful that we could change their diet to something less valuable to humanity," Love suggests. "For example, organic wastes from agriculture or even sewage."

Exactly how the E. coli microbes expel the diesel fuel molecules is unknown at this point. The researchers have found them floating in the growth medium, suggesting the microbes are somehow secreting the hydrocarbons from their cells once produced. "We don't know how they get there yet," Love admits. But that may solve a problem posed to other would-be biofuels produced in microbes; algal oils have proved difficult to extract cheaply and effectively from inside the algae themselves, among other challenges.

Besides a better grasp of the process itself, fine-tuning the genetic engineering may one day yield other useful hydrocarbons, such as jet fuel or even gasoline (a short-chained hydrocarbon). Similar work at the University of California, Berkeley, has tinkered with E. coli genetics to allow the bacteria to digest the inedible parts of plants known as cellulose and turn them into microbial diesel that can be used in place of fossil-fuel diesel or other useful hydrocarbons. And E. coli has been harnessed in the past to make specialty oils for cosmetics; the company Amyris makes the moisturizing oil known as squalane from E. coli fed sugarcane and grown in vats in Brazil. The synthetic biologists at Amyris have also coaxed yeast to produce the antimalarial drug artemisinin, a technology that is currently being commercialized with drugmaker Sanofi.

Regardless, industrial-scale fuel production from microbes remains a much tougher proposition than making specialty oils or medicines, given the low cost and high volumes required to compete with the fuels made from fossil sources. "Fuel is actually a lot cheaper than artemisinin, so it has to be made in significantly larger quantities," Love notes. "That in itself is a challenge."

Source: http://rss.sciam.com/click.phdo?i=4cddaf5a21b5a5d4dda63c21773cb607

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PFT: Several teams in top 12 look to move down

Tampa Bay Buccaneers v New Orleans SaintsGetty Images

It?s setting up to be a big season for Buccaneers quarterback Josh Freeman.

He?s on the last year of the deal he signed as a first-round pick in 2009 and his team just swung a big trade to raise expectations for a team that hasn?t made the playoffs since Freeman arrived. On top of all that, there were some mixed messages from coach Greg Schiano early in the offseason about his commitment to Freeman.

Schiano?s since said stronger things about the quarterback and Freeman says that he ?isn?t concerned? about what he calls a great relationship with the head coach. Freeman said the only thing that concerned him was taking the Bucs to the playoffs, whether or not he returns to the team in 2014.

?I give it all I got regardless,? Freeman said, via Rick Stroud of the Tampa Bay Times. ?I love football, I love my teammates, I love winning. It doesn?t really change anything for me. Obviously I love being a Buccaneer. But at the same time, the job is to go out and find a way to win and worrying about any sort of external forces, contract, all this stuff, you can?t worry about that. It?s not going to help you play better. You?ve got to focus on the things that will help you go out on Sundays and win.?

Freeman?s had his ups and downs through his first four seasons, with last year?s strong middle ? 16 touchdowns and three interceptions during a 5-1 stretch that briefly had the Bucs in the playoff hunt ? surrounded by less impressive work on either side. Freeman wasn?t the reason they missed the playoffs, a terrible pass defense had plenty to do with that, but there?s no doubt they?ll need more from Freeman as well if they?re going to make the playoffs in 2013.

Should that happen, Freeman probably won?t wind up any more concerned about the other stuff than he is now.

Source: http://profootballtalk.nbcsports.com/2013/04/23/report-five-teams-in-top-12-want-to-move-down/related/

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Saturday, February 23, 2013

George Washington is born

On this day in 1732, George Washington is born in Westmoreland County, Virginia, the second son from the second marriage of a colonial plantation owner. An initially loyal British subject, Washington eventually led the Continental Army in the American Revolution and became known as the father of the United States.

Washington rose to eminence on his own merit. His first job at age 17 was as a surveyor in the Shenandoah Valley. In 1752, he joined the British army and served as a lieutenant in the French and Indian War. When the war ended, Washington left the army and returned home to Virginia to manage Mount Vernon, the plantation he had recently inherited upon the death of his older brother. He married a wealthy widow, Martha Dandridge Custis, in 1759. Although the couple had no children, Washington adopted Martha's son and daughter from her previous marriage. While in Virginia, Washington served in the colonial House of Burgesses and, like many of his compatriots, grew increasingly frustrated with the British government. He soon joined his co-revolutionaries in the Continental Congress.

In 1775, the Continental Congress unanimously chose Washington to command the new Continental Army. In addition to advocating civilian control over the military, Washington possessed that intangible quality of a born leader and had earned a reputation for coolness under fire and as a strict disciplinarian during the French and Indian campaign. In that war, he dodged bullets, had horses shot out from under him and was even taken prisoner by the French. Part of his success in the Revolutionary War was due to his shrewd use of what was then considered the ungentlemanly, but effective, tactic of guerrilla warfare, in which stealthy hit-and-run attacks foiled British armies used to close-formation battle-line warfare. Although Washington led almost as many losing battles as he won, his successes at Trenton, Princeton and Yorktown proved pivotal for the Continental Army and the emerging nation. In 1789, in part because of the leadership skills he displayed during the war, the Continental Congress elected Washington as the first American president.

George Washington's legacy has endured a long process of untangling myth from fact. The famous cherry tree incident never occurred, nor did Washington have wooden teeth, though he did have only one tooth by the time he became president and wore a series of dentures made from metal and cow or hippopotamus bone. In portraits of Washington, the pain caused by his dentures is evident in his facial expression. Known for being emotionally reserved and aloof, Washington was concerned with personal conduct, character and self-discipline, but was known to bend the rules if necessary, especially in war. Although Washington was undoubtedly ambitious, he pursued his goals humbly and with quiet confidence in his abilities as a leader.

An extraordinary figure in American history and unusually tall at 6' 3, Washington was also an ordinary man. He loved cricket and fox-hunting, moved gracefully around a ballroom, was a Freemason and possibly a Deist, and was an astute observer of the darker side of human nature. His favorite foods were pineapples, Brazil nuts (hence the missing teeth from cracking the shells) and Saturday dinners of salt cod. He possessed a wry sense of humor and, like his wife Martha, tried to resist the vanities of public life. Washington could also explode into a rage when vexed in war or political battles. Loyal almost to a fault, he could also be unforgiving and cold when crossed. When Republican Thomas Jefferson admitted to slandering the president in an anonymous newspaper article for his support of Federalist Alexander Hamilton's policies, Washington cut Jefferson out of his life. On at least one occasion, Washington's stubbornness inspired John Adams to refer to him as Old Muttonhead.

An unenthusiastic political leader, Washington nevertheless recognized his unique and symbolic role in keeping a fledgling nation together. He worked hard to reconcile competing factions within his administration and was keenly aware of setting unwritten rules of conduct for future presidents. He struggled with advisors over what sort of image a president should project. He preferred one of dignity and humility and stumbled when encouraged to act out of character or monarchical. After two terms, old, tired, and disillusioned with vicious partisan politics, he resigned. His granddaughter remembered him as a prisoner of his own celebrity. Abigail Adams described Washington as having a dignity which forbids familiarity mixed with an easy affability which creates love and reverence.

After leaving office, Washington returned to Mount Vernon, indulged his passion for the rural life and started a successful whiskey distillery. A member of the Virginia planter class, he grew increasingly uncomfortable with the hypocrisy of owning slaves, yet publicly he promoted a gradual abolition of slavery. In his will he requested that his slaves be freed upon Martha's death. Although he and Martha had a good relationship, the great love of his life was Sally Fairfax, the wife of his friend George. Abandoning his characteristic self-control, Washington wrote to Sally toward the end of his life, confessing that his moments with her had been the happiest of his life.

On December 14, 1799, Washington died of a severe respiratory ailment. He humbly identified himself in his will as George Washington, of Mount Vernon, a citizen of the United States.

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Source: http://www.history.com/this-day-in-history/george-washington-is-born

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